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Then, we applied our previously proposed drug repositioning method which aims to repurpose useful drugs for targeting a specific gene based on the similarity analysis of the perturbations induced by the target gene knockdown and candidate drug treatment on the available human cell lines [13, 18]

[DOI] [PubMed] [Google Scholar] 42.Kapate N., Clegg J.R., Mitragotri S

3503-C A PHASE 2a, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE SAFETY, TOLERABILITY, EFFICACY, AND PHARMACOKINETICS OF INT-787 IN SUBJECTS WITH SEVERE ALCOHOL-ASSOCIATED HEPATITIS: STUDY DESIGN, OBJECTIVES, AND NOVEL ASSESSMENTS Thomas Capozza, Steven Lauder, Sam Madison and Jennifer Callahan, Intercept Pharmaceuticals, Inc., Morristown, NJ Background: Severe alcohol-associated hepatitis (sAH) is the most acute and serious form of alcohol-associated liver disease

Slit1 protein regulates SVZ-derived precursor mobilization in the adult demyelinated CNS

C.PatelS.et al

While KPV has shown promise in preliminary studies, the FDA requires more comprehensive data before allowing its widespread use in compounded medications